At least six people have died after a huge fire raged through the night at a west London 24-storey tower block, and police expect that number to rise.
Eyewitnesses described people trapped in the burning Grenfell Tower, in north Kensington, screaming for help and yelling for their children to be saved.
Firefighters, who rescued many people, were called at 00:54 BST and are still trying to put out the fire.
Police say there may still be people in the building who are unaccounted for.
The ambulance service said 69 patients had been taken to six hospitals across London, with 18 in critical care. A further 10 patients made their own way to hospital.
During the night, eyewitnesses said they saw lights – thought to be mobile phones or torches – flashing at the top of the block of flats, and trapped residents coming to their windows – some holding children.
It is understood that "several hundred" people would have been in the block when the fire broke out shortly after midnight, most of them sleeping.
Commander Stuart Cundy, of the Metropolitan Police, said the recovery operation would be "complex and lengthy", and the number of fatalities was expected to rise.
He declined to give any details of the number of people who may be missing.
He said it was likely to be some time before police could identify the victims, adding that it was too early to speculate on the cause of the fire.
Prime Minister Theresa May is "deeply saddened by the tragic loss of life", said Downing Street.
Health Secretary Jeremy Hunt praised the "heroic" response from the emergency services and the NHS hospital staff "working tirelessly to help".
Meanwhile, Labour leader Jeremy Corbyn is to demand a government statement in Parliament on Thursday on the tragedy, the BBC understands.
There must be a "full inquiry" into the fire, newly-elected Kensington MP Emma Dent Coad told the BBC.